{"id":210877,"date":"2025-04-08T10:22:45","date_gmt":"2025-04-08T15:22:45","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/abstract-why-are-so-many-patients-with-pancreatic-cancer-resistant-to-immunotherapy"},"modified":"2025-04-08T10:22:45","modified_gmt":"2025-04-08T15:22:45","slug":"abstract-why-are-so-many-patients-with-pancreatic-cancer-resistant-to-immunotherapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/abstract-why-are-so-many-patients-with-pancreatic-cancer-resistant-to-immunotherapy","title":{"rendered":"Abstract: Why are so many patients with pancreatic cancer resistant to immunotherapy?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract7.jpg\"><\/a><\/p>\n<p>Xueli Bai &amp; team report on the high level of lactate in pancreatic cancer metabolism, which changes tumor immune features by protein lactylation and results in immunotherapy resistance:<\/p>\n<p>The figure shows lactylation labeling of metabolic proteins from paracancerous and tumor tissues.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine and.<\/p>\n<p><sup>2<\/sup>Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.<\/p>\n<p><sup>3<\/sup>MOE Joint International Research Laboratory of Pancreatic Diseases, Hangzhou, China.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Xueli Bai &amp; team report on the high level of lactate in pancreatic cancer metabolism, which changes tumor immune features by protein lactylation and results in immunotherapy resistance: The figure shows lactylation labeling of metabolic proteins from paracancerous and tumor tissues. 1Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine and. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-210877","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/210877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=210877"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/210877\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=210877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=210877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=210877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}