{"id":210395,"date":"2025-04-02T13:13:17","date_gmt":"2025-04-02T18:13:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/live-cell-labeling-sheds-light-on-how-our-dna-is-packed-and-behaves-in-cells"},"modified":"2025-04-02T13:13:17","modified_gmt":"2025-04-02T18:13:17","slug":"live-cell-labeling-sheds-light-on-how-our-dna-is-packed-and-behaves-in-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/live-cell-labeling-sheds-light-on-how-our-dna-is-packed-and-behaves-in-cells","title":{"rendered":"Live-cell labeling sheds light on how our DNA is packed and behaves in cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/live-cell-labeling-sheds-light-on-how-our-dna-is-packed-and-behaves-in-cells2.jpg\"><\/a><\/p>\n<p>A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their distinct physical properties. They <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adu8400\" target=\"_blank\">published<\/a> their approach and findings on March 28 in Science Advances.<\/p>\n<p>Inside every human cell, 2 meters of DNA must be tightly packed into a tiny nucleus. This DNA is wrapped around proteins to form chromatin, which exists in two main forms: euchromatin, where genes are active, and heterochromatin, where <a href=\"https:\/\/phys.org\/tags\/gene+activity\/\" rel=\"tag\" class=\"\">gene activity<\/a> is suppressed.<\/p>\n<p>\u201cHow these two types of chromatin are organized and behave inside living cells is still not well understood,\u201d says Katsuhiko Minami, the first author of this study. \u201cUntil now, we lacked a way to specifically label euchromatin and heterochromatin in <a href=\"https:\/\/phys.org\/tags\/live+cells\/\" rel=\"tag\" class=\"\">live cells<\/a>.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their distinct physical properties. They published their approach and findings on March 28 in Science Advances. Inside every human cell, 2 meters of DNA must [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-210395","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/210395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=210395"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/210395\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=210395"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=210395"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=210395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}