{"id":209941,"date":"2025-03-28T10:09:23","date_gmt":"2025-03-28T15:09:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/modulating-mtor-dependent-astrocyte-substate-transitions-to-alleviate-neurodegeneration"},"modified":"2025-03-28T10:09:23","modified_gmt":"2025-03-28T15:09:23","slug":"modulating-mtor-dependent-astrocyte-substate-transitions-to-alleviate-neurodegeneration","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/modulating-mtor-dependent-astrocyte-substate-transitions-to-alleviate-neurodegeneration","title":{"rendered":"Modulating mTOR-dependent astrocyte substate transitions to alleviate neurodegeneration"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/modulating-mtor-dependent-astrocyte-substate-transitions-to-alleviate-neurodegeneration.jpg\"><\/a><\/p>\n<p>The authors show that neuroprotective and neurotoxic astrocytes representional cellular substates present during neuroinflammation and that targeting mTOR in astrocytes reduces neurotoxicity, suggesting a potential therapeutic strategy for neurodegenerative diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The authors show that neuroprotective and neurotoxic astrocytes representional cellular substates present during neuroinflammation and that targeting mTOR in astrocytes reduces neurotoxicity, suggesting a potential therapeutic strategy for neurodegenerative diseases.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-209941","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=209941"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209941\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=209941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=209941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=209941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}