{"id":209425,"date":"2025-03-21T11:21:24","date_gmt":"2025-03-21T16:21:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/boosting-brains-waste-removal-system-improves-memory-in-old-mice"},"modified":"2025-03-21T11:21:24","modified_gmt":"2025-03-21T16:21:24","slug":"boosting-brains-waste-removal-system-improves-memory-in-old-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/boosting-brains-waste-removal-system-improves-memory-in-old-mice","title":{"rendered":"Boosting brain\u2019s waste removal system improves memory in old mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/boosting-brains-waste-removal-system-improves-memory-in-old-mice.jpg\"><\/a><\/p>\n<p>As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer\u2019s disease and Parkinson\u2019s disease, among others.<\/p>\n<p>Now, researchers at Washington University School of Medicine in St. Louis report they have found a way around that problem by targeting the network of vessels that drain waste from the brain. Rejuvenating those vessels, they have shown, improves memory in <a href=\"https:\/\/medicalxpress.com\/tags\/old+mice\/\" rel=\"tag\" class=\"\">old mice<\/a>.<\/p>\n<p>The study, <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(25)00210-7\" target=\"_blank\">published<\/a> online in the journal <i>Cell<\/i>, lays the groundwork to develop therapies for age-related <a href=\"https:\/\/medicalxpress.com\/tags\/cognitive+decline\/\" rel=\"tag\" class=\"\">cognitive decline<\/a> that overcome the challenges faced by conventional medications that struggle to pass through the <a href=\"https:\/\/medicalxpress.com\/tags\/blood-brain+barrier\/\" rel=\"tag\" class=\"\">blood-brain barrier<\/a> to reach the brain.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer\u2019s disease and Parkinson\u2019s disease, among others. Now, researchers at Washington University School of Medicine in St. Louis report they have found a way around that problem by [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-209425","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=209425"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209425\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=209425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=209425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=209425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}