{"id":209135,"date":"2025-03-19T09:22:18","date_gmt":"2025-03-19T14:22:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/antibiotic-resistant-bacteria-more-vulnerable-under-body-like-fluid-flow-conditions-study-finds"},"modified":"2025-03-19T09:22:18","modified_gmt":"2025-03-19T14:22:18","slug":"antibiotic-resistant-bacteria-more-vulnerable-under-body-like-fluid-flow-conditions-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/antibiotic-resistant-bacteria-more-vulnerable-under-body-like-fluid-flow-conditions-study-finds","title":{"rendered":"Antibiotic-resistant bacteria more vulnerable under body-like fluid flow conditions, study finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/antibiotic-resistant-bacteria-more-vulnerable-under-body-like-fluid-flow-conditions-study-finds.jpg\"><\/a><\/p>\n<p>Some notoriously difficult-to-treat infections may not be as resistant to antibiotics as has been thought, according to new research using a microfluidic device that more closely duplicates the fluid flow found in the body than standard cultures.<\/p>\n<p>The University of Illinois Urbana-Champaign research team, led by biochemistry professor Joe Sanfilippo, tested <a href=\"https:\/\/phys.org\/tags\/antibiotic+agents\/\" rel=\"tag\" class=\"\">antibiotic agents<\/a> against <i>Pseudomonas<\/i> aeruginosa, considered one of the most highly resistant pathogens. They introduced the drugs at varying rates of fluid flow and found that, while the bacteria thrived at no or low fluid flow, the antibiotics killed the bacteria at higher flow rates.<\/p>\n<p>\u201cAnytime you take an antibiotic orally or by IV, it\u2019s not immediately in the place it is supposed to be. It will get there by flowing in the bloodstream. Other fluids move throughout the body as well: in the lungs, the <a href=\"https:\/\/phys.org\/tags\/urinary+tract\/\" rel=\"tag\" class=\"\">urinary tract<\/a>, the digestive tract. Yet biologists don\u2019t really study the impact of fluid flow when they study pathogens,\u201d Sanfilippo said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some notoriously difficult-to-treat infections may not be as resistant to antibiotics as has been thought, according to new research using a microfluidic device that more closely duplicates the fluid flow found in the body than standard cultures. The University of Illinois Urbana-Champaign research team, led by biochemistry professor Joe Sanfilippo, tested antibiotic agents against Pseudomonas [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-209135","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=209135"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/209135\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=209135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=209135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=209135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}