{"id":208771,"date":"2025-03-15T11:15:51","date_gmt":"2025-03-15T16:15:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/anti-nephrin-autoantibodies-cause-a-podocytopathy-with-minimal-change-lesions"},"modified":"2025-03-15T11:15:51","modified_gmt":"2025-03-15T16:15:51","slug":"anti-nephrin-autoantibodies-cause-a-podocytopathy-with-minimal-change-lesions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/anti-nephrin-autoantibodies-cause-a-podocytopathy-with-minimal-change-lesions","title":{"rendered":"Anti-nephrin autoantibodies cause a podocytopathy with minimal change lesions"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/anti-nephrin-autoantibodies-cause-a-podocytopathy-with-minimal-change-lesions2.jpg\"><\/a><\/p>\n<p>Does autoimmunity underlie minimal change disease?<\/p>\n<p>Tobias B. Huber, Nicola M. Tomas &amp; team report a direct pathogenic role of anti-nephrin autoantibodies in the development of podocytopathy with a minimal change disease phenotype:<\/p>\n<p>The electron microscopy image shows moderate podocyte foot process effacement (without electron-dense deposits) in the anti-nephrin rabbit.<\/p>\n<hr>\n<p>Address correspondence to: Tobias B. Huber or Nicola M. Tomas, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany. Phone: 49.40.7410.53908; Email: <a href=\"mailto:t.huber@uke.de\">t.huber@uke.de<\/a> (TBH); <a href=\"mailto:n.tomas@uke.de\">n.tomas@uke.de<\/a> (NMT).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Does autoimmunity underlie minimal change disease? Tobias B. Huber, Nicola M. Tomas &amp; team report a direct pathogenic role of anti-nephrin autoantibodies in the development of podocytopathy with a minimal change disease phenotype: The electron microscopy image shows moderate podocyte foot process effacement (without electron-dense deposits) in the anti-nephrin rabbit. Address correspondence to: Tobias B. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1512],"tags":[],"class_list":["post-208771","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-mobile-phones"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=208771"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208771\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=208771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=208771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=208771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}