{"id":208429,"date":"2025-03-12T07:22:22","date_gmt":"2025-03-12T12:22:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/smartphone-and-nanotechnology-enable-rapid-neonatal-jaundice-detection"},"modified":"2025-03-12T07:22:22","modified_gmt":"2025-03-12T12:22:22","slug":"smartphone-and-nanotechnology-enable-rapid-neonatal-jaundice-detection","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/smartphone-and-nanotechnology-enable-rapid-neonatal-jaundice-detection","title":{"rendered":"Smartphone and nanotechnology enable rapid neonatal jaundice detection"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/smartphone-and-nanotechnology-enable-rapid-neonatal-jaundice-detection3.jpg\"><\/a><\/p>\n<p>A research team led by Prof. Jiang Changlong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has developed an innovative dual-mode sensing platform using upconversion nanoparticles (UCNPs). This platform integrates fluorescence and colorimetric methods, offering a highly sensitive and low-detection-limit solution for bilirubin detection in complex biological samples.<\/p>\n<p>The findings, <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.4c05839\" target=\"_blank\">published<\/a> in <i>Analytical Chemistry<\/i>, offer a new technological approach for the early diagnosis of jaundice.<\/p>\n<p>Jaundice is a critical health issue in neonates, affecting 60% of newborns and contributing to early neonatal mortality. Elevated free bilirubin levels indicate jaundice, with healthy levels ranging from 1.7 \u03bcM to 10.2 \u03bcM in healthy individuals. Concentrations below 32 \u03bcM typically don\u2019t show classic symptoms. Rapid and accurate detection of bilirubin in neonates is critical.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A research team led by Prof. Jiang Changlong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has developed an innovative dual-mode sensing platform using upconversion nanoparticles (UCNPs). This platform integrates fluorescence and colorimetric methods, offering a highly sensitive and low-detection-limit solution for bilirubin detection in complex biological samples. The findings, [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,1495,1512,4],"tags":[],"class_list":["post-208429","post","type-post","status-publish","format-standard","hentry","category-biological","category-health","category-mobile-phones","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=208429"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208429\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=208429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=208429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=208429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}