{"id":208262,"date":"2025-03-10T11:12:24","date_gmt":"2025-03-10T16:12:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/03\/dietary-pro-oxidant-therapy-by-a-vitamin-k-precursor-targets-pi-3-kinase-vps34-function"},"modified":"2025-03-10T11:12:24","modified_gmt":"2025-03-10T16:12:24","slug":"dietary-pro-oxidant-therapy-by-a-vitamin-k-precursor-targets-pi-3-kinase-vps34-function","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/03\/dietary-pro-oxidant-therapy-by-a-vitamin-k-precursor-targets-pi-3-kinase-vps34-function","title":{"rendered":"Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dietary-pro-oxidant-therapy-by-a-vitamin-k-precursor-targets-pi-3-kinase-vps34-function2.jpg\"><\/a><\/p>\n<p>We finally have a more natural method to kill cancer.<\/p>\n<p>A study from Cold Spring Harbor Laboratory suggests that a vitamin K precursor, menadione, may offer a highly targeted way to kill prostate cancer cells.<\/p>\n<p>Unlike traditional treatments that push cancer into dormancy, menadione acts as a pro-oxidant, disrupting a key lipid called PIP. This lipid helps cells manage waste, and without it, cancer cells become overwhelmed and ultimately burst.<\/p>\n<p>The study, published in <i>Science<\/i>, demonstrated significant tumor suppression in both mice and human cancer cells. Researchers believe this method could offer a safer and more definitive resolution for prostate cancer while minimizing the risk of resistance.<\/p>\n<p>Beyond cancer, menadione also shows promise in treating X-linked myotubular myopathy, a severe genetic muscle disorder. Importantly, menadione\u2019s safety profile appears favorable, as it is commonly used in animal feed to support vitamin K production.<\/p>\n<p>The findings suggest that menadione could be especially beneficial for prostate cancer patients under active surveillance, potentially delaying or even preventing progression.<\/p>\n<p>With low side effects and a highly selective approach, this research offers new hope for effective, minimally invasive cancer treatment options.<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2025\/03\/dietary-pro-oxidant-therapy-by-a-vitamin-k-precursor-targets-pi-3-kinase-vps34-function\">Continue reading \u201cDietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function\u201d | &gt;<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>We finally have a more natural method to kill cancer. A study from Cold Spring Harbor Laboratory suggests that a vitamin K precursor, menadione, may offer a highly targeted way to kill prostate cancer cells. Unlike traditional treatments that push cancer into dormancy, menadione acts as a pro-oxidant, disrupting a key lipid called PIP. This [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-208262","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=208262"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/208262\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=208262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=208262"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=208262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}