{"id":207246,"date":"2025-02-25T15:27:06","date_gmt":"2025-02-25T21:27:06","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/dysfunctional-cd11c%e2%88%92cd21%e2%88%92-extrafollicular-memory-b-cells-are-enriched-in-the-periphery-and-tumors-of-patients-with-cancer"},"modified":"2025-02-25T15:27:06","modified_gmt":"2025-02-25T21:27:06","slug":"dysfunctional-cd11c%e2%88%92cd21%e2%88%92-extrafollicular-memory-b-cells-are-enriched-in-the-periphery-and-tumors-of-patients-with-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/dysfunctional-cd11c%e2%88%92cd21%e2%88%92-extrafollicular-memory-b-cells-are-enriched-in-the-periphery-and-tumors-of-patients-with-cancer","title":{"rendered":"Dysfunctional CD11c\u2212CD21\u2212 extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dysfunctional-cd11ce28892cd21e28892-extrafollicular-memory-b-cells-are-enriched-in-the-periphery-and-tumors-of-patients-with-cancer2.jpg\"><\/a><\/p>\n<p>New findings cast light on the role of understudied DN3 memory B cells in cancer, and shows these cells correlate with progression and poor clinical outcomes in head and neck squamous cell carcinoma and melanoma.<\/p>\n<p>\ud83d\udcc4<\/p>\n<hr>\n<p>Tumor-associated extrafollicular B cells are phenotypically, locationally, and functionally distinct from germinal center\u2013dependent memory B cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New findings cast light on the role of understudied DN3 memory B cells in cancer, and shows these cells correlate with progression and poor clinical outcomes in head and neck squamous cell carcinoma and melanoma. \ud83d\udcc4 Tumor-associated extrafollicular B cells are phenotypically, locationally, and functionally distinct from germinal center\u2013dependent memory B cells.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-207246","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=207246"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207246\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=207246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=207246"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=207246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}