{"id":207214,"date":"2025-02-25T05:18:13","date_gmt":"2025-02-25T11:18:13","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/dna-origami-suggests-route-to-reusable-multifunctional-biosensors"},"modified":"2025-02-25T05:18:13","modified_gmt":"2025-02-25T11:18:13","slug":"dna-origami-suggests-route-to-reusable-multifunctional-biosensors","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/dna-origami-suggests-route-to-reusable-multifunctional-biosensors","title":{"rendered":"DNA origami suggests route to reusable, multifunctional biosensors"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dna-origami-suggests-route-to-reusable-multifunctional-biosensors2.jpg\"><\/a><\/p>\n<p>Using an approach called DNA origami, scientists at Caltech have developed a technique that could lead to cheaper, reusable biomarker sensors for quickly detecting proteins in bodily fluids, eliminating the need to send samples out to lab centers for testing.<\/p>\n<p>\u201cOur work provides a proof-of-concept showing a path to a single-step method that could be used to identify and measure <a href=\"https:\/\/phys.org\/tags\/nucleic+acids\/\" rel=\"tag\" class=\"\">nucleic acids<\/a> and proteins,\u201d says Paul Rothemund (BS \u201894), a visiting associate at Caltech in computing and mathematical sciences, and computation and neural systems.<\/p>\n<p>A paper describing the work recently <a href=\"https:\/\/pnas.org\/doi\/10.1073\/pnas.2311279121\" target=\"_blank\">appeared<\/a> in the journal <i>Proceedings of the National Academy of Sciences<\/i>. The lead authors of the paper are former Caltech postdoctoral scholar Byoung-jin Jeon and current graduate student Matteo M. Guareschi, who completed the work in Rothemund\u2019s lab.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using an approach called DNA origami, scientists at Caltech have developed a technique that could lead to cheaper, reusable biomarker sensors for quickly detecting proteins in bodily fluids, eliminating the need to send samples out to lab centers for testing. \u201cOur work provides a proof-of-concept showing a path to a single-step method that could be [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523,2229,47],"tags":[],"class_list":["post-207214","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing","category-mathematics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=207214"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207214\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=207214"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=207214"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=207214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}