{"id":207109,"date":"2025-02-24T05:16:47","date_gmt":"2025-02-24T11:16:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/a-stressed-mind-is-made-more-prone-to-rigid-thinking-mouse-study-finds"},"modified":"2025-02-24T05:16:47","modified_gmt":"2025-02-24T11:16:47","slug":"a-stressed-mind-is-made-more-prone-to-rigid-thinking-mouse-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/a-stressed-mind-is-made-more-prone-to-rigid-thinking-mouse-study-finds","title":{"rendered":"A stressed mind is made more prone to rigid thinking, mouse study finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-stressed-mind-is-made-more-prone-to-rigid-thinking-mouse-study-finds2.jpg\"><\/a><\/p>\n<p>University of California, Los Angeles researchers have discovered that chronic stress flips brain activity between two amygdala-striatal pathways, disrupting flexible decision-making and promoting inflexible habits.<\/p>\n<p>The research identifies distinct roles for the <a href=\"https:\/\/medicalxpress.com\/tags\/basolateral+amygdala\/\" rel=\"tag\" class=\"\">basolateral amygdala <\/a>\u2013dorsomedial striatum (BLA\u2192DMS) and central amygdala\u2013dorsomedial striatum (CeA\u2192DMS) circuits in action-outcome learning and habit formation.<\/p>\n<p>Chronic stress impairs goal-directed decision-making, often leading to rigid, habitual behaviors that underpin several psychiatric conditions. Understanding the <a href=\"https:\/\/medicalxpress.com\/tags\/neuronal+circuits\/\" rel=\"tag\" class=\"\">neuronal circuits<\/a> involved could illuminate vulnerabilities in disorders like substance use, <a href=\"https:\/\/medicalxpress.com\/tags\/obsessive-compulsive+disorder\/\" rel=\"tag\" class=\"\">obsessive-compulsive disorder<\/a>, and depression.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of California, Los Angeles researchers have discovered that chronic stress flips brain activity between two amygdala-striatal pathways, disrupting flexible decision-making and promoting inflexible habits. The research identifies distinct roles for the basolateral amygdala \u2013dorsomedial striatum (BLA\u2192DMS) and central amygdala\u2013dorsomedial striatum (CeA\u2192DMS) circuits in action-outcome learning and habit formation. Chronic stress impairs goal-directed decision-making, often [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-207109","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=207109"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207109\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=207109"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=207109"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=207109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}