{"id":207035,"date":"2025-02-23T13:05:27","date_gmt":"2025-02-23T19:05:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/scientists-uncover-new-way-cancer-evades-the-bodys-defenses"},"modified":"2025-02-23T13:05:27","modified_gmt":"2025-02-23T19:05:27","slug":"scientists-uncover-new-way-cancer-evades-the-bodys-defenses","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/scientists-uncover-new-way-cancer-evades-the-bodys-defenses","title":{"rendered":"Scientists Uncover New Way Cancer Evades the Body\u2019s Defenses"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-uncover-new-way-cancer-evades-the-bodys-defenses.jpg\"><\/a><\/p>\n<p>The immune system is essential for identifying and eliminating cancer cells. Cancer immunotherapy enhances this process by training immune cells to recognize and attack tumors. However, many cancers develop mechanisms to evade immune detection, leading to resistance to treatment. Understanding the molecular basis of this immune evasion is crucial for improving therapeutic strategies.<\/p>\n<p>The tumor microenvironment (TME)\u2014the area surrounding a tumor\u2014plays a pivotal role in interactions between cancer and immune cells. Cancer cells can manipulate the TME to suppress tumor-infiltrating lymphocytes (TILs), the immune cells responsible for attacking tumors. Mitochondria, often called the \u201cpowerhouse of the cell,\u201d generate energy for various cellular functions and play a key role in the metabolic reprogramming of both cancer cells and TILs. However, the exact mechanisms of mitochondrial dysfunction and its impact on the TME remain poorly understood.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The immune system is essential for identifying and eliminating cancer cells. Cancer immunotherapy enhances this process by training immune cells to recognize and attack tumors. However, many cancers develop mechanisms to evade immune detection, leading to resistance to treatment. Understanding the molecular basis of this immune evasion is crucial for improving therapeutic strategies. The tumor [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-207035","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207035","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=207035"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/207035\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=207035"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=207035"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=207035"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}