{"id":206976,"date":"2025-02-21T21:15:35","date_gmt":"2025-02-22T03:15:35","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/genetic-regulation-of-tert-splicing-affects-cancer-risk-by-altering-cellular-longevity-and-replicative-potential"},"modified":"2025-02-21T21:15:35","modified_gmt":"2025-02-22T03:15:35","slug":"genetic-regulation-of-tert-splicing-affects-cancer-risk-by-altering-cellular-longevity-and-replicative-potential","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/genetic-regulation-of-tert-splicing-affects-cancer-risk-by-altering-cellular-longevity-and-replicative-potential","title":{"rendered":"Genetic regulation of TERT splicing affects cancer risk by altering cellular longevity and replicative potential"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/genetic-regulation-of-tert-splicing-affects-cancer-risk-by-altering-cellular-longevity-and-replicative-potential.jpg\"><\/a><\/p>\n<p>Several multi-cancer GWAS loci within the region encoding telomerase reverse transcriptase (TERT) have been identified. Here, the authors explore the locus within TERT intron 4, link it with a variable number tandem repeat (VNTR), and investigate its biological significance and role in cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Several multi-cancer GWAS loci within the region encoding telomerase reverse transcriptase (TERT) have been identified. Here, the authors explore the locus within TERT intron 4, link it with a variable number tandem repeat (VNTR), and investigate its biological significance and role in cancer.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-206976","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206976","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=206976"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206976\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=206976"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=206976"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=206976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}