{"id":20687,"date":"2016-01-12T15:14:13","date_gmt":"2016-01-12T23:14:13","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/?p=20687"},"modified":"2017-04-24T23:04:02","modified_gmt":"2017-04-25T06:04:02","slug":"where-will-advanced-brain-mapping-lead-us","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/01\/where-will-advanced-brain-mapping-lead-us","title":{"rendered":"Where Will Advanced Brain Mapping Lead Us?"},"content":{"rendered":"<p><span style=\"font-weight: 400\">In the early days of the space race of the 1960s, NASA used satellites to map the geography of the moon. A better understanding of its geology, however, came when men actually walked on the moon, culminating with Astronaut and Geologist Harrison Schmitt exploring the moon\u2019s surface during the Apollo 17 mission in 1972.<\/span><\/p> Image credit: Scientific American <p><span style=\"font-weight: 400\">In the modern era, <\/span><a href=\"http:\/\/techemergence.com\/episode-85-what-would-it-take-to-model-the-human-mind-computational-neuroanatomy-with-dr-gregory-hickok\/\"><span style=\"font-weight: 400\">Dr. Gregory Hickock<\/span><\/a><span style=\"font-weight: 400\"> is one neuroscientist who believes the field of neuroscience is pursuing comparable advances. While scientists have historically developed a geographic map of the brain\u2019s functional systems, Hickock says computational neuroanatomy is digging deeper into the geology of the brain to help provide an understanding of how the different regions interact computationally to give rise to complex behaviors.<\/span><\/p>\n<p>\u201cComputational neuroanatomy is kind of working towards that level of description from the brain map perspective. The typical function maps you see in textbooks are cartoon-like. We\u2019re trying to take those mountain areas and, instead of relating them to labels for functions like language, we\u2019re trying to map them on \u2014 and relate them to \u2014 stuff that the computational neuroscientists are doing.\u201d<\/p>\n<p><span style=\"font-weight: 400\">Hickok pointed to a number of advances that have already been made through computational neuroanatomy: mapping visual systems to determine how the visual cortex can code information and perform computations, as well as mapping neurally realistic approximations of circuits that actually mimic motor control, among others. In addition, researchers are building <\/span><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0893608097000117\"><span style=\"font-weight: 400\">spiking network models<\/span><\/a><span style=\"font-weight: 400\">, which simulate individual neurons. Scientists use thousands of these neurons in simulations to operate robots in a manner comparable to how the brain might perform the job. <\/span><\/p>\n<p><span style=\"font-weight: 400\">That research is driving more innovation in artificial intelligence, says Gregory. For example, brain-inspired models are being used to develop better AI systems for stores of information or retrieval of information, as well as in automated speech recognition systems. In addition, this sort of work can be used to develop better cochlear implants or other sorts of neural-prostheses, which are just starting to be explored. <\/span><\/p>\n<p>\u201cIn terms of neural-prostheses that can take advantage of this stuff, if you look at patterns and activity in neurons or regions in cortex, you can decode information from those patterns of activity, (such as) motor plans or acoustic representation,\u201d Hickok said. \u201cSo it\u2019s possible now to implant an electrode array in the motor cortex of an individual who is locked in, so to speak, and they can control a robotic arm.\u201d<\/p>\n<p><span style=\"font-weight: 400\">More specifically, Hickok is interested in <\/span><a href=\"http:\/\/www.nature.com\/nrn\/journal\/v13\/n2\/full\/nrn3158.html\"><span style=\"font-weight: 400\">applying computational neuroanatomy to speech and language functions<\/span><\/a><span style=\"font-weight: 400\">. In some cases where patients have lost the ability to produce fluid speech, he states that the cause is the disconnection of still-intact brain areas that are no longer \u201ctalking to each other\u201d. Once we understand how these circuits are organized and what they\u2019re doing computationally, Gregory believes we might one day be able to insert electrode arrays and reconnect those brain areas as a form of rehabilitation. <\/span><\/p>\n<p><span style=\"font-weight: 400\">As he looks at the future applications in artificial intelligence, Hickok says he expects continued development in neural-prostheses, such as cochlear implants, artificial retinas, and artificial motor control circuits. The fact that scientists are still trying to simulate how the brain does its computations is one hurdle; the \u201csquishy\u201d nature of brain matter seems to operate differently than the precision developed in digital computers. <\/span><\/p>\n<p><span style=\"font-weight: 400\">Though multiple global brain projects are underway and progress is being made (Wired\u2019s Katie Palmer gives a <a href=\"http:\/\/www.wired.com\/2015\/05\/first-big-step-toward-mapping-human-brain\/\">succinct overview<\/a>), Gregory emphasizes that we\u2019re still nowhere close to actually re-creating the human mind. <\/span><span style=\"font-weight: 400\">\u201cPresumably, this is what evolution has done over millions of years to configure systems that allow us to do lots of different things and that is going to (sic) take a really long time to figure out,\u201d he said. \u201cThe number of neurons involved, 80 billion in the current estimate, trillions of connections, lots and lots of moving parts, different strategies for coding different kinds of computations\u2026 it\u2019s just ridiculously complex and I don\u2019t see that as something that\u2019s easily going to give up its secrets within the next couple of generations.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the early days of the space race of the 1960s, NASA used satellites to map the geography of the moon. A better understanding of its geology, however, came when men actually walked on the moon, culminating with Astronaut and Geologist Harrison Schmitt exploring the moon\u2019s surface during the Apollo 17 mission in 1972. In [\u2026]<\/p>\n","protected":false},"author":274,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1965,47,6],"tags":[2334,2331,2330,2333,2332,2335],"class_list":["post-20687","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-mapping","category-neuroscience","category-robotics-ai","tag-building-human-brain","tag-computational-neuroanatomy","tag-gregory-hickock","tag-mapping-the-brain","tag-neural-prostheses","tag-spiking-network-models"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/274"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=20687"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20687\/revisions"}],"predecessor-version":[{"id":44583,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20687\/revisions\/44583"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=20687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=20687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=20687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}