{"id":206620,"date":"2025-02-17T13:12:15","date_gmt":"2025-02-17T19:12:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/chromatin-fibers-genomic-memory-governs-the-building-blocks-of-life-study-reveals"},"modified":"2025-02-17T13:12:15","modified_gmt":"2025-02-17T19:12:15","slug":"chromatin-fibers-genomic-memory-governs-the-building-blocks-of-life-study-reveals","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/chromatin-fibers-genomic-memory-governs-the-building-blocks-of-life-study-reveals","title":{"rendered":"Chromatin fiber\u2019s genomic \u2018memory\u2019 governs the building blocks of life, study reveals"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/chromatin-fibers-genomic-memory-governs-the-building-blocks-of-life-study-reveals2.jpg\"><\/a><\/p>\n<p>Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering new study <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adq6652\" target=\"_blank\">published<\/a> in Science Advances.<\/p>\n<p>While it\u2019s understood that genes function as a set of instructions for creating RNA, and thus proteins and cells, the fundamental process by which this occurs has not been well-studied due to technological limitations, said Vadim Backman, Ph.D., the Sachs Family Professor of Biomedical Engineering and Medicine, who was senior author of the study.<\/p>\n<p>\u201cIt is still not fully understood how, despite having the same set of genes, cells turn into neurons, bones, skin, heart, or roughly 200 other kinds of cells, and then exhibit stable cellular behavior over a human lifespan which can last for more than a century\u2014or why aging degrades this process,\u201d said Backman, who directs the Center for Physical Genomics and Engineering at Northwestern. \u201cThis has been a long-standing open question in biology.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering new study published in Science Advances. While it\u2019s understood that genes function as a set of instructions for creating RNA, and thus proteins and cells, the fundamental [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,269,47],"tags":[],"class_list":["post-206620","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=206620"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206620\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=206620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=206620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=206620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}