{"id":206389,"date":"2025-02-13T19:02:24","date_gmt":"2025-02-14T01:02:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/scientists-just-rewrote-our-understanding-of-epigenetics"},"modified":"2025-02-13T19:02:24","modified_gmt":"2025-02-14T01:02:24","slug":"scientists-just-rewrote-our-understanding-of-epigenetics","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/scientists-just-rewrote-our-understanding-of-epigenetics","title":{"rendered":"Scientists just rewrote our understanding of epigenetics"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-just-rewrote-our-understanding-of-epigenetics.jpg\"><\/a><\/p>\n<p>If the coordination of DNA and RNA epigenetics gets thrown off, you may end up with too much or too little of a protein, Fuk suggested. \u201cNow, a key protein will be expressed at a too high level,\u201d he said.\u201d This could be detrimental for a cell and contribute to tumorigenesis,\u201d or the formation of tumors.<\/p>\n<p>There are already approved therapies that inhibit the methylation of DNA, and there\u2019s an early-phase clinical trial testing RNA methylation inhibition as a cancer treatment. Fuks and his team are testing the potential of combining these existing therapies to improve patients\u2019 outcomes. Preliminary data from their laboratory studies hint this strategy could be useful for patients with leukemia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>If the coordination of DNA and RNA epigenetics gets thrown off, you may end up with too much or too little of a protein, Fuk suggested. \u201cNow, a key protein will be expressed at a too high level,\u201d he said.\u201d This could be detrimental for a cell and contribute to tumorigenesis,\u201d or the formation of [\u2026]<\/p>\n","protected":false},"author":599,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-206389","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/599"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=206389"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/206389\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=206389"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=206389"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=206389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}