{"id":205879,"date":"2025-02-08T03:14:09","date_gmt":"2025-02-08T09:14:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/neural-pathway-in-mice-sheds-light-on-how-the-brain-regulates-learned-immune-responses"},"modified":"2025-02-08T03:14:09","modified_gmt":"2025-02-08T09:14:09","slug":"neural-pathway-in-mice-sheds-light-on-how-the-brain-regulates-learned-immune-responses","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/neural-pathway-in-mice-sheds-light-on-how-the-brain-regulates-learned-immune-responses","title":{"rendered":"Neural pathway in mice sheds light on how the brain regulates learned immune responses"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/neural-pathway-in-mice-sheds-light-on-how-the-brain-regulates-learned-immune-responses2.jpg\"><\/a><\/p>\n<p>The brain of humans and other animals is known to contribute to the protection of the body from infections. Past studies have unveiled the existence of the so-called conditioned immune response (CIR), which is a form of Pavlovian conditioning that entails the formation of mental associations between specific sensory stimuli (e.g., a specific odor, taste, etc.) and immunomodulatory agents (i.e., a substance that influences the immune system).<\/p>\n<p>For instance, if an animal tastes a particular food shortly before becoming ill several times, re-experiencing the same taste can evoke an aversive response and even trigger an anticipatory immune response. While this CIR is now well-documented, its <a href=\"https:\/\/medicalxpress.com\/tags\/neural+underpinnings\/\" rel=\"tag\" class=\"\">neural underpinnings<\/a> so far remain poorly understood.<\/p>\n<p>Researchers at University of Haifa recently carried out a study aimed at better understanding the <a href=\"https:\/\/medicalxpress.com\/tags\/neural+pathways\/\" rel=\"tag\" class=\"\">neural pathways<\/a> involved in these widely reported conditioned immune responses (CIRs). Their paper, published in <i>Nature Neuroscience<\/i>, <a href=\"https:\/\/www.nature.com\/articles\/s41593-024-01864-4\" target=\"_blank\">outlines a neural pathway<\/a> that appears to mediate the retrieval of CIRs in male mice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The brain of humans and other animals is known to contribute to the protection of the body from infections. Past studies have unveiled the existence of the so-called conditioned immune response (CIR), which is a form of Pavlovian conditioning that entails the formation of mental associations between specific sensory stimuli (e.g., a specific odor, taste, [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1506,47],"tags":[],"class_list":["post-205879","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-food","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205879","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=205879"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205879\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=205879"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=205879"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=205879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}