{"id":205720,"date":"2025-02-06T08:24:24","date_gmt":"2025-02-06T14:24:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/molecular-switch-reverses-cancerous-transformation-at-the-critical-moment-of-transition"},"modified":"2025-02-06T08:24:24","modified_gmt":"2025-02-06T14:24:24","slug":"molecular-switch-reverses-cancerous-transformation-at-the-critical-moment-of-transition","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/molecular-switch-reverses-cancerous-transformation-at-the-critical-moment-of-transition","title":{"rendered":"Molecular switch reverses cancerous transformation at the critical moment of transition"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/molecular-switch-reverses-cancerous-transformation-at-the-critical-moment-of-transition2.jpg\"><\/a><\/p>\n<p>Professor Kwang-Hyun Cho\u2019s research team of the Department of Bio and Brain Engineering at KAIST has captured the critical transition phenomenon at the moment when normal cells change into cancer cells and analyzed it to discover a molecular switch hidden in the genetic network that can revert cancer cells back into normal cells.<\/p>\n<p>The team\u2019s findings are <a href=\"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.202412503\" target=\"_blank\">published<\/a> in the journal Advanced Science.<\/p>\n<p>A critical transition is a phenomenon in which a sudden change in state occurs at a specific point in time, like water changing into steam at 100\u2103. This critical transition phenomenon also occurs in the process in which <a href=\"https:\/\/phys.org\/tags\/normal+cells\/\" rel=\"tag\" class=\"\">normal cells<\/a> change into <a href=\"https:\/\/phys.org\/tags\/cancer+cells\/\" rel=\"tag\" class=\"\">cancer cells<\/a> at a specific point in time due to the accumulation of genetic and <a href=\"https:\/\/phys.org\/tags\/epigenetic+changes\/\" rel=\"tag\" class=\"\">epigenetic changes<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Kwang-Hyun Cho\u2019s research team of the Department of Bio and Brain Engineering at KAIST has captured the critical transition phenomenon at the moment when normal cells change into cancer cells and analyzed it to discover a molecular switch hidden in the genetic network that can revert cancer cells back into normal cells. The team\u2019s [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412,47],"tags":[],"class_list":["post-205720","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=205720"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205720\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=205720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=205720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=205720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}