{"id":205415,"date":"2025-02-03T23:44:50","date_gmt":"2025-02-04T05:44:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/02\/safe-bioink-for-artificial-organ-printing"},"modified":"2025-02-03T23:44:50","modified_gmt":"2025-02-04T05:44:50","slug":"safe-bioink-for-artificial-organ-printing","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/02\/safe-bioink-for-artificial-organ-printing","title":{"rendered":"Safe bioink for artificial organ printing"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/safe-bioink-for-artificial-organ-printing3.jpg\"><\/a><\/p>\n<p>The development of biomaterials for artificial organs and tissues is an active area of research due to increases in accidental injuries and chronic diseases, along with the entry into a super-aged society. 3D bioprinting technology, which uses cells and biomaterials to create three-dimensional artificial tissue structures, has recently gained popularity. However, commonly used hydrogel-based bioinks can cause cytotoxicity due to the chemical crosslinking agent and ultraviolet light that connect the molecular structure of photocuring 3D-printed bioink.<\/p>\n<p>Dr. Song Soo-chang\u2019s research team at the Center for Biomaterials, Korea Institute of Science and Technology (KIST), revealed the first development of poly(organophosphazene) hydrogel-based temperature-sensitive <a href=\"https:\/\/phys.org\/tags\/bioink\/\" rel=\"tag\" class=\"\">bioink<\/a> that stably maintained its physical structure by temperature control only without photocuring, induced tissue regeneration, and then biodegraded in the body after a certain period of time.<\/p>\n<p>Current hydrogel-based bioinks must go through a photocuring process to enhance the mechanical properties of the 3D scaffold after printing, with a high risk of adverse effects in the human body. In addition, there has been a possibility of side effects when transplanting externally cultured cells within bioink to increase the tissue regeneration effect.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The development of biomaterials for artificial organs and tissues is an active area of research due to increases in accidental injuries and chronic diseases, along with the entry into a super-aged society. 3D bioprinting technology, which uses cells and biomaterials to create three-dimensional artificial tissue structures, has recently gained popularity. However, commonly used hydrogel-based bioinks [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1489,1503,11,19],"tags":[],"class_list":["post-205415","post","type-post","status-publish","format-standard","hentry","category-3d-printing","category-bioprinting","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205415","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=205415"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/205415\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=205415"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=205415"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=205415"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}