{"id":20523,"date":"2016-01-07T12:01:26","date_gmt":"2016-01-07T20:01:26","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/01\/new-synthetic-molecular-prosthetic-cell-acts-as-and-gate-for-disease-treatment"},"modified":"2017-06-04T20:16:39","modified_gmt":"2017-06-05T03:16:39","slug":"new-synthetic-molecular-prosthetic-cell-acts-as-and-gate-for-disease-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/01\/new-synthetic-molecular-prosthetic-cell-acts-as-and-gate-for-disease-treatment","title":{"rendered":"New synthetic molecular prosthetic cell acts as AND gate for disease treatment"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/new-synthetic-molecular-prosthetic-cell-acts-as-and-gate-for-disease-treatment.jpg\"><\/a><\/p>\n<p>And the Singularity rolls ever on. And on.<\/p>\n<hr>\n<p>\u201cCytokine converter\u201d AND-gate synthetic-biology prosthesis used to treat psoriasis in mice. Top left: skin before; right: skin after. (credit: Lina Schukur et al.\/Science Translational Medicine) <\/p>\n<p>An advanced \u201cmolecular prosthetic\u201d \u2014 a cell with synthetic gene circuits that can be implanted into an organism to take over metabolic functions that the organism cannot perform itself \u2014 has been developed by <a href=\"https:\/\/www.ethz.ch\/\" target=\"_blank\">ETH Zurich<\/a> scientists.<\/p>\n<p>Previous gene circuits typically monitored only whether one disease-causing molecule (called a cytokine) was present in their environment and if so, produced a single therapeutic cytokine as a response. The new \u201ccytokine converter\u201d synthetic circuit functions like an AND gate: It can detect two different cytokines simultaneously, and if (and only if) both are present, produces two different cytokines that can treat a disease.<\/p>\n<p><a href=\"http:\/\/www.kurzweilai.net\/new-synthetic-molecular-prosthetic-cell-acts-as-and-gate-for-disease-treatment\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>And the Singularity rolls ever on. And on. \u201cCytokine converter\u201d AND-gate synthetic-biology prosthesis used to treat psoriasis in mice. Top left: skin before; right: skin after. (credit: Lina Schukur et al.\/Science Translational Medicine) An advanced \u201cmolecular prosthetic\u201d \u2014 a cell with synthetic gene circuits that can be implanted into an organism to take over metabolic [\u2026]<\/p>\n","protected":false},"author":362,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1499,64],"tags":[],"class_list":["post-20523","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-cyborgs","category-singularity"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20523","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/362"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=20523"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20523\/revisions"}],"predecessor-version":[{"id":68907,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20523\/revisions\/68907"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=20523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=20523"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=20523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}