{"id":20416,"date":"2016-01-03T17:47:30","date_gmt":"2016-01-04T01:47:30","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/01\/gene-editing-offers-hope-for-treating-duchenne-muscular-dystrophy-studies-find"},"modified":"2017-06-04T20:16:51","modified_gmt":"2017-06-05T03:16:51","slug":"gene-editing-offers-hope-for-treating-duchenne-muscular-dystrophy-studies-find","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/01\/gene-editing-offers-hope-for-treating-duchenne-muscular-dystrophy-studies-find","title":{"rendered":"Gene Editing Offers Hope for Treating Duchenne Muscular Dystrophy, Studies Find"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/gene-editing-offers-hope-for-treating-duchenne-muscular-dystrophy-studies-find.jpg\"><\/a><\/p>\n<p>Three research groups, working independently of one another, reported in the journal Science on Thursday that they had used the Crispr-Cas9 technique to treat mice with a defective dystrophin gene. Each group loaded the DNA-cutting system onto a virus that infected the mice\u2019s muscle cells, and excised from the gene a defective stretch of DNA known as an exon.<\/p>\n<p>Without the defective exon, the muscle cells made a shortened dystrophin protein that was nonetheless functional, giving all of the mice more strength.<\/p>\n<p>The teams were led by Charles A. Gersbach of Duke University, Eric N. Olson of the University of Texas Southwestern Medical Center and Amy J. Wagers of Harvard University.<\/p>\n<p><a href=\"http:\/\/www.nytimes.com\/2016\/01\/01\/science\/gene-therapy-muscular-dystrophy.html?hpw&rref=science&action=click&pgtype=Homepage&module=well-region&region=bottom-well&WT.nav=bottom-well&_r=0\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Three research groups, working independently of one another, reported in the journal Science on Thursday that they had used the Crispr-Cas9 technique to treat mice with a defective dystrophin gene. Each group loaded the DNA-cutting system onto a virus that infected the mice\u2019s muscle cells, and excised from the gene a defective stretch of DNA [\u2026]<\/p>\n","protected":false},"author":384,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-20416","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20416","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/384"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=20416"}],"version-history":[{"count":3,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20416\/revisions"}],"predecessor-version":[{"id":68926,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20416\/revisions\/68926"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=20416"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=20416"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=20416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}