{"id":204141,"date":"2025-01-20T19:24:00","date_gmt":"2025-01-21T01:24:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/01\/enhancing-nad-efficiency-by-energizing-sirtuins"},"modified":"2025-01-20T19:24:00","modified_gmt":"2025-01-21T01:24:00","slug":"enhancing-nad-efficiency-by-energizing-sirtuins","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/01\/enhancing-nad-efficiency-by-energizing-sirtuins","title":{"rendered":"Enhancing NAD+ Efficiency by Energizing Sirtuins"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enhancing-nad-efficiency-by-energizing-sirtuins.jpg\"><\/a><\/p>\n<p>Researchers publishing in <i>Physical Review X<\/i> have discovered <a href=\"https:\/\/journals.aps.org\/prx\/abstract\/10.1103\/PhysRevX.14.041019\">compounds that can double the efficiency of the sirtuin SIRT3 in processing NAD+<\/a>.<\/p>\n<p><b><b>Looking for a new way to boost enzymes<\/b><\/b><\/p>\n<p>The researchers begin their paper by noting that most drugs administered to people are geared towards inhibition of particular enzymes in order to treat a disease. In this case, however, the goal is the opposite: to boost the function of an enzyme, thereby boosting a healthy phenotype rather than battling back a diseased one.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers publishing in Physical Review X have discovered compounds that can double the efficiency of the sirtuin SIRT3 in processing NAD+. Looking for a new way to boost enzymes The researchers begin their paper by noting that most drugs administered to people are geared towards inhibition of particular enzymes in order to treat a disease. [\u2026]<\/p>\n","protected":false},"author":692,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-204141","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/204141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/692"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=204141"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/204141\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=204141"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=204141"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=204141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}