{"id":203955,"date":"2025-01-17T11:28:54","date_gmt":"2025-01-17T17:28:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/01\/intracerebroventricular-b7-h3-targeting-car-t-cells-for-diffuse-intrinsic-pontine-glioma-a-phase-1-trial"},"modified":"2025-01-17T11:28:54","modified_gmt":"2025-01-17T17:28:54","slug":"intracerebroventricular-b7-h3-targeting-car-t-cells-for-diffuse-intrinsic-pontine-glioma-a-phase-1-trial","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/01\/intracerebroventricular-b7-h3-targeting-car-t-cells-for-diffuse-intrinsic-pontine-glioma-a-phase-1-trial","title":{"rendered":"Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/intracerebroventricular-b7-h3-targeting-car-t-cells-for-diffuse-intrinsic-pontine-glioma-a-phase-1-trial.jpg\"><\/a><\/p>\n<p>In the final report of a phase 1 trial evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from diagnosis.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the final report of a phase 1 trial evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from diagnosis.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-203955","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=203955"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203955\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=203955"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=203955"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=203955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}