{"id":203029,"date":"2025-01-03T10:27:19","date_gmt":"2025-01-03T16:27:19","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/01\/detecting-disease-with-a-single-molecule-nanopore-based-sensors-could-transform-diagnostics"},"modified":"2025-01-03T10:27:19","modified_gmt":"2025-01-03T16:27:19","slug":"detecting-disease-with-a-single-molecule-nanopore-based-sensors-could-transform-diagnostics","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/01\/detecting-disease-with-a-single-molecule-nanopore-based-sensors-could-transform-diagnostics","title":{"rendered":"Detecting disease with a single molecule: Nanopore-based sensors could transform diagnostics"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/detecting-disease-with-a-single-molecule-nanopore-based-sensors-could-transform-diagnostics.jpg\"><\/a><\/p>\n<p>UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.<\/p>\n<p>Since the molecules scientists want to detect\u2014generally certain DNA or protein molecules\u2014are roughly one-billionth of a meter wide, the <a href=\"https:\/\/phys.org\/tags\/electrical+signals\/\" rel=\"tag\" class=\"\">electrical signals<\/a> they produce are very small and require specialized detection instruments.<\/p>\n<p>\u201cRight now, you need millions of molecules to detect diseases. We\u2019re showing that it\u2019s possible to get useful data from just a <a href=\"https:\/\/phys.org\/tags\/single+molecule\/\" rel=\"tag\" class=\"\">single molecule<\/a>,\u201d said Kevin Freedman, assistant professor of bioengineering at UCR and lead author of a paper about the tool <a href=\"https:\/\/www.nature.com\/articles\/s41565-024-01829-5\" target=\"_blank\">appearing<\/a> in <i>Nature Nanotechnology.<\/i> \u201cThis level of sensitivity could make a real difference in disease diagnostics.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules. Since the molecules scientists want to detect\u2014generally certain DNA or protein molecules\u2014are roughly one-billionth of a meter wide, the electrical signals they produce are very small [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-203029","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=203029"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203029\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=203029"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=203029"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=203029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}