{"id":203028,"date":"2025-01-03T10:27:05","date_gmt":"2025-01-03T16:27:05","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/01\/aging-hotspot-found-in-the-brain-may-hold-the-key-to-longevity"},"modified":"2025-01-03T10:27:05","modified_gmt":"2025-01-03T16:27:05","slug":"aging-hotspot-found-in-the-brain-may-hold-the-key-to-longevity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/01\/aging-hotspot-found-in-the-brain-may-hold-the-key-to-longevity","title":{"rendered":"\u2018Aging hotspot\u2019 found in the brain may hold the key to longevity"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/aging-hotspot-found-in-the-brain-may-hold-the-key-to-longevity3.jpg\"><\/a><\/p>\n<p>Researchers at the Allen Institute have identified a specific brain region in mice where aging triggers significant changes in numerous cell types. The study also pinpointed which cell types undergo the most profound transformations.<\/p>\n<p>This new information, published in the journal <a href=\"http:\/\/dx.doi.org\/10.1038\/s41586-024-08350-8\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Nature<\/em><\/a>, points toward potential approaches for slowing or controlling the <a href=\"https:\/\/www.earth.com\/news\/what-25-years-of-research-revealed-about-brain-aging\/\" target=\"_blank\" rel=\"noreferrer noopener\">aging<\/a> process in the brain.<\/p>\n<p>The research was focused on numerous glial cell types \u2013 the brain\u2019s \u201csupport cells\u201d \u2013 that demonstrated considerable shifts in gene activity with age. Among the cells most affected were microglia, border-associated macrophages, oligodendrocytes, tanycytes, and ependymal cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the Allen Institute have identified a specific brain region in mice where aging triggers significant changes in numerous cell types. The study also pinpointed which cell types undergo the most profound transformations. This new information, published in the journal Nature, points toward potential approaches for slowing or controlling the aging process in the [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269,47],"tags":[],"class_list":["post-203028","post","type-post","status-publish","format-standard","hentry","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=203028"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/203028\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=203028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=203028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=203028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}