{"id":202250,"date":"2024-12-23T18:07:48","date_gmt":"2024-12-24T00:07:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/12\/ai-that-can-design-lifes-machinery-from-scratch-had-a-big-year-heres-what-happens-next"},"modified":"2024-12-23T18:07:48","modified_gmt":"2024-12-24T00:07:48","slug":"ai-that-can-design-lifes-machinery-from-scratch-had-a-big-year-heres-what-happens-next","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/12\/ai-that-can-design-lifes-machinery-from-scratch-had-a-big-year-heres-what-happens-next","title":{"rendered":"AI That Can Design Life\u2019s Machinery From Scratch Had a Big Year. Here\u2019s What Happens Next"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ai-that-can-design-lifes-machinery-from-scratch-had-a-big-year-heres-what-happens-next2.jpg\"><\/a><\/p>\n<p><a href=\"https:\/\/singularityhub.com\/2024\/04\/25\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch\/\">One<\/a> used AI to dream up a universe of potential CRISPR gene editors. Inspired by large language models\u2014like those that gave birth to ChatGPT\u2014the AI model in the study eventually designed a gene editing system as accurate as existing CRISPR-based tools when tested on cells. <a href=\"https:\/\/singularityhub.com\/2024\/06\/17\/scientists-show-ai-generated-proteins-actually-work-in-stem-cell-study\/\">Another AI designed<\/a> circle-shaped proteins that reliably turned stem cells into different blood vessel cell types. Other <a href=\"https:\/\/www.nature.com\/articles\/s41586-024-07948-2\">AI-generated proteins<\/a> directed protein \u201cjunk\u201d into the lysosome, a waste treatment blob filled with acid inside cells that keeps them neat and tidy.<\/p>\n<p>Outside of medicine, AI designed <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-43608-1\">mineral-forming proteins<\/a> that, if integrated into aquatic microbes, could potentially soak up excess carbon and transform it into limestone. While still early, the technology could tackle climate change with a carbon sink that lasts millions of years.<\/p>\n<p>It seems imagination is the only limit to AI-based protein design. But there are still a few cases that AI can\u2019t yet fully handle. <a href=\"https:\/\/www.nature.com\/articles\/d41586-024-03595-9\"><em>Nature<\/em> has a comprehensive list<\/a><em>,<\/em> but these stand out.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One used AI to dream up a universe of potential CRISPR gene editors. Inspired by large language models\u2014like those that gave birth to ChatGPT\u2014the AI model in the study eventually designed a gene editing system as accurate as existing CRISPR-based tools when tested on cells. Another AI designed circle-shaped proteins that reliably turned stem cells [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,6],"tags":[],"class_list":["post-202250","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=202250"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202250\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=202250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=202250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=202250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}