{"id":20215,"date":"2015-12-24T14:31:23","date_gmt":"2015-12-24T22:31:23","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2015\/12\/new-genes-associated-with-extreme-longevity-identified"},"modified":"2017-06-04T20:17:16","modified_gmt":"2017-06-05T03:17:16","slug":"new-genes-associated-with-extreme-longevity-identified","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2015\/12\/new-genes-associated-with-extreme-longevity-identified","title":{"rendered":"New genes associated with extreme longevity identified"},"content":{"rendered":"<p><a class=\\'blog-photo\\' href=\"https:\/\/lifeboat.com\/blog.images\/new-genes-associated-with-extreme-longevity-identified.jpg\"><\/a><\/p>\n<p>Death is a disease.<\/p>\n<p>Diseases can and will be cured.<\/p>\n<p>Do the math. <span class=\"wp-smiley emoji emoji-wink\" title=\";-)\">wink<\/span>  <\/p>\n<hr>\n<p>\n<b>Disease GWAS show substantial genetic overlap with longevity. Shown are results for coronary artery disease and Alzheimer\u2019s disease. The y axis is the observed P values for longevity, and the x axis is the expected P values under the null hypothesis that the disease is independent of longevity. The cyan, blue and purple lines show the P values for longevity of the top 100, 250, and 500 disease SNPs from independent genetic loci, respectively. Red lines show the background distribution of longevity P values for all independent genetic loci tested in both the longevity and disease GWAS. The grey horizontal line corresponds to the threshold for nominal significance (P = 0.05) for longevity. Significance of enrichment was determined with the hypergeometric test. (credit: Kristen Fortney et al.\/PLOS Genetics)<\/b><\/p>\n<p>What\u2019s the secret of centenarians who have health and diet habits similar to the average person but have remained active and alert at very old ages?<\/p>\n<p>Genes. That\u2019s according to scientists at <a href=\"https:\/\/www.stanford.edu\/\" target=\"_blank\">Stanford University<\/a> and the <a href=\"http:\/\/www.unibo.it\/en\" target=\"_blank\">University of Bologna<\/a>, who have written a new report published in <em>PLOS Genetics<\/em>, based on their finding of several disease variants that may be absent in centenarians compared to the general population.<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2015\/12\/new-genes-associated-with-extreme-longevity-identified\">Continue reading \u201cNew genes associated with extreme longevity identified\u201d | &gt;<\/a><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Death is a disease. Diseases can and will be cured. Do the math. wink Disease GWAS show substantial genetic overlap with longevity. Shown are results for coronary artery disease and Alzheimer\u2019s disease. The y axis is the observed P values for longevity, and the x axis is the expected P values under the null hypothesis [\u2026]<\/p>\n","protected":false},"author":362,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1495,269,2229,47],"tags":[],"class_list":["post-20215","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-health","category-life-extension","category-mathematics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/362"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=20215"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20215\/revisions"}],"predecessor-version":[{"id":68969,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/20215\/revisions\/68969"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=20215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=20215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=20215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}