{"id":202078,"date":"2024-12-21T06:13:48","date_gmt":"2024-12-21T12:13:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/12\/experimental-drug-that-summons-warriors-of-the-immune-system-shows-early-promise-against-non-hodgkin-lymphoma"},"modified":"2024-12-21T06:13:48","modified_gmt":"2024-12-21T12:13:48","slug":"experimental-drug-that-summons-warriors-of-the-immune-system-shows-early-promise-against-non-hodgkin-lymphoma","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/12\/experimental-drug-that-summons-warriors-of-the-immune-system-shows-early-promise-against-non-hodgkin-lymphoma","title":{"rendered":"Experimental drug that summons \u2018warriors of the immune system\u2019 shows early promise against non-Hodgkin lymphoma"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/experimental-drug-that-summons-warriors-of-the-immune-system-shows-early-promise-against-non-hodgkin-lymphoma3.jpg\"><\/a><\/p>\n<p>An investigational therapy is demonstrating preclinical promise against non-Hodgkin lymphoma by boosting natural killer cells and efficiently annihilating the malignancy without toxicity to the patient, a team of cancer biologists in France has found.<\/p>\n<p>The emerging <a href=\"https:\/\/medicalxpress.com\/tags\/therapy\/\" rel=\"tag\" class=\"\">therapy<\/a> is for B cell non-Hodgkin lymphoma, the most common form of lymphoma worldwide. Current therapies target the CD20<sup>+<\/sup> protein on the surface of cancerous B cells but with limited efficacy. A newly developed antibody-based molecule targets B-non-Hodgkin lymphoma by engaging <a href=\"https:\/\/medicalxpress.com\/tags\/natural+killer+cells\/\" rel=\"tag\" class=\"\">natural killer cells<\/a>, warriors of the immune system. The experimental therapeutic is expected to help patients whose disease rebounds and is difficult to treat.<\/p>\n<p>\u201cNon-Hodgkin lymphoma is the most frequent hematological malignancy in humans, comprising nearly 3% of all <a href=\"https:\/\/medicalxpress.com\/tags\/cancer\/\" rel=\"tag\" class=\"\">cancer<\/a> diagnoses and oncology-related mortalities,\u201d writes Dr. Olivier Demaria, lead author of the research <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciimmunol.adp3720\" target=\"_blank\">published<\/a> in Science Immunology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An investigational therapy is demonstrating preclinical promise against non-Hodgkin lymphoma by boosting natural killer cells and efficiently annihilating the malignancy without toxicity to the patient, a team of cancer biologists in France has found. The emerging therapy is for B cell non-Hodgkin lymphoma, the most common form of lymphoma worldwide. Current therapies target the CD20+ [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-202078","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=202078"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202078\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=202078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=202078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=202078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}