{"id":202029,"date":"2024-12-20T14:41:18","date_gmt":"2024-12-20T20:41:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/12\/spatial-transcriptomic-clocks-reveal-local-cellular-interactions-influence-brain-aging"},"modified":"2024-12-20T14:41:18","modified_gmt":"2024-12-20T20:41:18","slug":"spatial-transcriptomic-clocks-reveal-local-cellular-interactions-influence-brain-aging","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/12\/spatial-transcriptomic-clocks-reveal-local-cellular-interactions-influence-brain-aging","title":{"rendered":"Spatial Transcriptomic Clocks Reveal Local Cellular Interactions Influence Brain Aging"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/spatial-transcriptomic-clocks-reveal-local-cellular-interactions-influence-brain-aging2.jpg\"><\/a><\/p>\n<p>Certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage. Using spatial transcriptomics and AI, researchers at Stanford\u2019s Knight Initiative for Brain Resilience discovered these interactions playing out across the lifespan\u2014suggesting local cellular interactions may significantly influence brain aging and resilience.<\/p>\n<p>A new study was published in <em>Nature <\/em>in an article titled, \u201c<a href=\"https:\/\/dx.doi.org\/10.1038\/s41586-024-08334-8\">Spatial transcriptomic clocks reveal cell proximity effects in brain aging<\/a>.\u201d<\/p>\n<p>\u201cWhat was exciting to us was finding that some cells have a pro-aging effect on neighboring cells while others appear to have a rejuvenating effect on their neighbors,\u201d said Anne Brunet, the Michele and Timothy Barakett Endowed Professor in Stanford\u2019s department of genetics and co-senior investigator of the new study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage. Using spatial transcriptomics and AI, researchers at Stanford\u2019s Knight Initiative for Brain Resilience discovered these interactions playing out across the lifespan\u2014suggesting local cellular interactions may significantly influence brain aging and resilience. A [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,269,6],"tags":[],"class_list":["post-202029","post","type-post","status-publish","format-standard","hentry","category-genetics","category-life-extension","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=202029"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/202029\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=202029"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=202029"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=202029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}