{"id":201370,"date":"2024-12-12T06:47:25","date_gmt":"2024-12-12T12:47:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/12\/unexpected-shifts-in-cell-populations-revise-understanding-of-aging-process"},"modified":"2024-12-12T06:47:25","modified_gmt":"2024-12-12T12:47:25","slug":"unexpected-shifts-in-cell-populations-revise-understanding-of-aging-process","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/12\/unexpected-shifts-in-cell-populations-revise-understanding-of-aging-process","title":{"rendered":"Unexpected shifts in cell populations revise understanding of aging process"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/unexpected-shifts-in-cell-populations-revise-understanding-of-aging-process2.jpg\"><\/a><\/p>\n<p>If you looked at two snapshots of the same maple tree taken in July and December, you\u2019d see a dramatic change from summer\u2019s full green crown to winter\u2019s bare branches. What those two photos don\u2019t show you, however, is how the change occurred\u2014gradually or all at once? In truth, deciduous trees tend to hold out for an environmental signal\u2014a change in light or temperature\u2014and then shed all their leaves within just a week or two.<\/p>\n<p>When it comes to aging, we may be more like these trees than we realized.<\/p>\n<p>According to new work from Rockefeller\u2019s Laboratory of Single-Cell Genomics and Population Dynamics, mammals follow a similar aging trajectory at the cellular level. As described in a <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adn3949\" target=\"_blank\">new paper<\/a> in <i>Science<\/i>, lab head Junyue Cao and his colleagues used single-cell sequencing to simultaneously scan more than 21 million cells from every major mouse organ across five stages of life. This enormous collection is now the world\u2019s largest cellular atlas within a single study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you looked at two snapshots of the same maple tree taken in July and December, you\u2019d see a dramatic change from summer\u2019s full green crown to winter\u2019s bare branches. What those two photos don\u2019t show you, however, is how the change occurred\u2014gradually or all at once? In truth, deciduous trees tend to hold out [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-201370","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/201370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=201370"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/201370\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=201370"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=201370"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=201370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}