{"id":200290,"date":"2024-11-27T17:26:20","date_gmt":"2024-11-27T23:26:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/11\/molecular-and-genetic-insights-into-human-ovarian-aging-from-single-nuclei-multi-omics-analyses"},"modified":"2024-11-27T17:26:20","modified_gmt":"2024-11-27T23:26:20","slug":"molecular-and-genetic-insights-into-human-ovarian-aging-from-single-nuclei-multi-omics-analyses","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/11\/molecular-and-genetic-insights-into-human-ovarian-aging-from-single-nuclei-multi-omics-analyses","title":{"rendered":"Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/molecular-and-genetic-insights-into-human-ovarian-aging-from-single-nuclei-multi-omics-analyses2.jpg\"><\/a><\/p>\n<p>The molecular and cellular mechanisms underlying ovarian aging are incompletely understood. Here the authors provide single-nuclei RNA and ATAC-seq of human ovarian tissue from four young and four reproductively aged donors, revealing coordinated transcriptomic and epigenomic changes across cell types and highlighting a role for mTOR signaling in reproductive aging.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The molecular and cellular mechanisms underlying ovarian aging are incompletely understood. Here the authors provide single-nuclei RNA and ATAC-seq of human ovarian tissue from four young and four reproductively aged donors, revealing coordinated transcriptomic and epigenomic changes across cell types and highlighting a role for mTOR signaling in reproductive aging.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,269],"tags":[],"class_list":["post-200290","post","type-post","status-publish","format-standard","hentry","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/200290","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=200290"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/200290\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=200290"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=200290"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=200290"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}