{"id":200132,"date":"2024-11-25T13:22:32","date_gmt":"2024-11-25T19:22:32","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/11\/a-bioinspired-capsule-can-pump-drugs-directly-into-the-walls-of-the-gi-tract"},"modified":"2024-11-25T13:22:32","modified_gmt":"2024-11-25T19:22:32","slug":"a-bioinspired-capsule-can-pump-drugs-directly-into-the-walls-of-the-gi-tract","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/11\/a-bioinspired-capsule-can-pump-drugs-directly-into-the-walls-of-the-gi-tract","title":{"rendered":"A bioinspired capsule can pump drugs directly into the walls of the GI tract"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-bioinspired-capsule-can-pump-drugs-directly-into-the-walls-of-the-gi-tract2.jpg\"><\/a><\/p>\n<p>This capsule\u2026<\/p>\n<hr>\n<p>Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.<\/p>\n<p>This capsule could offer an alternative way to deliver drugs that normally have to be injected, such as insulin and other large proteins, including antibodies. This needle-free strategy could also be used to deliver RNA, either as a vaccine or a therapeutic molecule to treat diabetes, obesity, and other metabolic disorders.<\/p>\n<p>\u201cOne of the longstanding challenges that we\u2019ve been exploring is the development of systems that enable the oral delivery of macromolecules that usually require an injection to be administered. This work represents one of the next major advances in that progression,\u201d says Giovanni Traverso, director of the Laboratory for Translational Engineering and an associate professor of mechanical engineering at MIT, a gastroenterologist at Brigham and Women\u2019s Hospital, an associate member of the Broad Institute, and the senior author of the study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This capsule\u2026 Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract. This capsule could offer [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-200132","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/200132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=200132"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/200132\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=200132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=200132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=200132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}