{"id":199341,"date":"2024-11-12T16:25:25","date_gmt":"2024-11-12T22:25:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/11\/chemists-create-impossible-bond-in-molecule-defying-100-year-old-rule"},"modified":"2024-11-12T16:25:25","modified_gmt":"2024-11-12T22:25:25","slug":"chemists-create-impossible-bond-in-molecule-defying-100-year-old-rule","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/11\/chemists-create-impossible-bond-in-molecule-defying-100-year-old-rule","title":{"rendered":"Chemists Create \u2018Impossible\u2019 Bond in Molecule, Defying 100-Year-Old Rule"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/chemists-create-impossible-bond-in-molecule-defying-100-year-old-rule2.jpg\"><\/a><\/p>\n<p>Carbon is a gregarious little atom, bending over backwards to link with a wide variety of elements in what is collectively referred to as organic chemistry. Life itself wouldn\u2019t be possible without <a href=\"https:\/\/www.sciencealert.com\/this-radical-experiment-shows-how-life-s-chemistry-could-have-begun-in-deep-space\">carbon\u2019s knack for making connections<\/a>.<\/p>\n<p>Yet even this friendly fellow has its limits. Take <a href=\"https:\/\/en.wikipedia.org\/wiki\/Bredt%27s_rule\">Bredt\u2019s rule<\/a> for instance, which says stable two-laned connections known as covalent double bonds won\u2019t form adjacent to any V-shaped bridges that happen to form across \u2018<a href=\"https:\/\/en.wikipedia.org\/wiki\/Bicyclic_molecule\">bicyclic\u2019 molecules<\/a>.<\/p>\n<p>Now a team of chemists from the University of California, Los Angeles has uncovered a solution that violates Bredt\u2019s century-old rule. This encourages future drug research to explore the use of molecules that we thought could not exist.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Carbon is a gregarious little atom, bending over backwards to link with a wide variety of elements in what is collectively referred to as organic chemistry. Life itself wouldn\u2019t be possible without carbon\u2019s knack for making connections. Yet even this friendly fellow has its limits. Take Bredt\u2019s rule for instance, which says stable two-laned connections [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-199341","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/199341","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=199341"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/199341\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=199341"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=199341"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=199341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}