{"id":199307,"date":"2024-11-12T08:22:33","date_gmt":"2024-11-12T14:22:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/11\/induced-pluripotent-stem-cell-derived-macrophages-as-a-platform-for-modelling-human-disease"},"modified":"2024-11-12T08:22:33","modified_gmt":"2024-11-12T14:22:33","slug":"induced-pluripotent-stem-cell-derived-macrophages-as-a-platform-for-modelling-human-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/11\/induced-pluripotent-stem-cell-derived-macrophages-as-a-platform-for-modelling-human-disease","title":{"rendered":"Induced pluripotent stem cell-derived macrophages as a platform for modelling human disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/induced-pluripotent-stem-cell-derived-macrophages-as-a-platform-for-modelling-human-disease.jpg\"><\/a><\/p>\n<p>Macrophages are associated with many human diseases but are challenging to study in vivo. Here, Ginhoux and colleagues discuss how iMacs \u2014 macrophages generated from induced pluripotent stem (iPS) cells \u2014 can enable disease modelling, including through the use of patient-derived iPS cells and 3D organoid co-culture systems. Ultimately, these iMac-based approaches can improve our understanding of macrophage biology in both health and disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Macrophages are associated with many human diseases but are challenging to study in vivo. Here, Ginhoux and colleagues discuss how iMacs \u2014 macrophages generated from induced pluripotent stem (iPS) cells \u2014 can enable disease modelling, including through the use of patient-derived iPS cells and 3D organoid co-culture systems. Ultimately, these iMac-based approaches can improve our [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-199307","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/199307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=199307"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/199307\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=199307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=199307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=199307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}