{"id":198653,"date":"2024-11-01T10:26:34","date_gmt":"2024-11-01T15:26:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/11\/scientists-successfully-reverse-liver-fibrosis-in-mice"},"modified":"2024-11-01T10:26:34","modified_gmt":"2024-11-01T15:26:34","slug":"scientists-successfully-reverse-liver-fibrosis-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/11\/scientists-successfully-reverse-liver-fibrosis-in-mice","title":{"rendered":"Scientists successfully reverse liver fibrosis in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-successfully-reverse-liver-fibrosis-in-mice2.jpg\"><\/a><\/p>\n<p>Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis\u2014a potentially lethal stiffening of tissue that, once begun, is irreversible. For many patients, a liver transplant is their only hope. However, research at Cedars-Sinai in Los Angeles may offer patients a glimmer of hope. Scientists there say they\u2019ve successfully reversed liver fibrosis in mice.<\/p>\n<p>Reporting in the journal <a href=\"https:\/\/www.nature.com\/articles\/s41467-024-52527-8\" target=\"_blank\"><i>Nature Communications<\/i><\/a>, the team say they\u2019ve discovered a genetic pathway that, if blocked, might bring fibrosis to a halt.<\/p>\n<p>The three genes involved in this fibrotic process are called FOXM1, MAT2A and MAT2B.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis\u2014a potentially lethal stiffening of tissue that, once begun, is irreversible. For many patients, a liver transplant is their only hope. However, research at Cedars-Sinai in Los Angeles may offer patients a glimmer of hope. Scientists there say they\u2019ve successfully reversed liver fibrosis in mice. Reporting [\u2026]<\/p>\n","protected":false},"author":579,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-198653","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/198653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/579"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=198653"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/198653\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=198653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=198653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=198653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}