{"id":196823,"date":"2024-09-30T17:22:28","date_gmt":"2024-09-30T22:22:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/09\/mit-scientists-use-a-new-type-of-nanoparticle-to-make-vaccines-more-powerful"},"modified":"2024-09-30T17:22:28","modified_gmt":"2024-09-30T22:22:28","slug":"mit-scientists-use-a-new-type-of-nanoparticle-to-make-vaccines-more-powerful","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/09\/mit-scientists-use-a-new-type-of-nanoparticle-to-make-vaccines-more-powerful","title":{"rendered":"MIT scientists use a new type of nanoparticle to make vaccines more powerful"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mit-scientists-use-a-new-type-of-nanoparticle-to-make-vaccines-more-powerful.jpg\"><\/a><\/p>\n<p>Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins.<\/p>\n<hr>\n<p>\u201cNot only are we delivering the protein in a more controlled way through a nanoparticle, but the compositional structure of this particle is also acting as an adjuvant,\u201d Jaklenec says. \u201cWe were able to achieve very specific responses to the Covid protein, and with a dose-sparing effect compared to using the protein by itself to vaccinate.\u201d<\/p>\n<p><strong>Vaccine access<\/strong><\/p>\n<p>While this study and others have demonstrated ZIF-8\u2019s immunogenic ability, more work needs to be done to evaluate the particles\u2019 safety and potential to be scaled up for large-scale manufacturing. If ZIF-8 is not developed as a vaccine carrier, the findings from the study should help to guide researchers in developing similar nanoparticles that could be used to deliver subunit vaccines, Jaklenec says.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. \u201cNot only are we delivering the protein in a more controlled way through a nanoparticle, but the compositional structure of this particle is also acting as an adjuvant,\u201d Jaklenec says. \u201cWe were able to achieve very specific [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4],"tags":[],"class_list":["post-196823","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/196823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=196823"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/196823\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=196823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=196823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=196823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}