{"id":196517,"date":"2024-09-21T21:23:41","date_gmt":"2024-09-22T02:23:41","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/09\/new-brain-organoid-model-replicates-human-cortical-domains"},"modified":"2024-09-21T21:23:41","modified_gmt":"2024-09-22T02:23:41","slug":"new-brain-organoid-model-replicates-human-cortical-domains","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/09\/new-brain-organoid-model-replicates-human-cortical-domains","title":{"rendered":"New brain organoid model replicates human cortical domains"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-brain-organoid-model-replicates-human-cortical-domains2.jpg\"><\/a><\/p>\n<p>The group of J\u00fcrgen Knoblich at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences, has developed a new method that allows scientists to cultivate brain organoids with distinct cortical areas and front-to-back patterning.<\/p>\n<p>Together with collaborators at the Human Technopole and the University of Milan-Bicocca, they report a method that gives scientists a deeper look into human-specific brain development and disorders. The study was <a href=\"https:\/\/www.nature.com\/articles\/s41592-024-02412-5\" target=\"_blank\">published<\/a> in <i>Nature Methods<\/i> on September 18.<\/p>\n<p>Brain organoids are extensively used to study <a href=\"https:\/\/medicalxpress.com\/tags\/human+brain\/\" rel=\"tag\" class=\"\">human brain<\/a> development. Derived from <a href=\"https:\/\/medicalxpress.com\/tags\/human+pluripotent+stem+cells\/\" rel=\"tag\" class=\"\">human pluripotent stem cells<\/a>, the 3D models allow scientists to study unique properties of the human brain. Researchers use cortical organoids to answer fundamental questions such as how the human brain can grow to its large size or how the human brain\u2019s long-range connections form.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The group of J\u00fcrgen Knoblich at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences, has developed a new method that allows scientists to cultivate brain organoids with distinct cortical areas and front-to-back patterning. Together with collaborators at the Human Technopole and the University of Milan-Bicocca, they report a method that gives [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-196517","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/196517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=196517"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/196517\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=196517"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=196517"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=196517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}