{"id":195994,"date":"2024-09-10T17:23:20","date_gmt":"2024-09-10T22:23:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/09\/cleaning-up-the-aging-brain"},"modified":"2024-09-10T17:23:20","modified_gmt":"2024-09-10T22:23:20","slug":"cleaning-up-the-aging-brain","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/09\/cleaning-up-the-aging-brain","title":{"rendered":"Cleaning up the aging brain"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cleaning-up-the-aging-brain3.jpg\"><\/a><\/p>\n<p>Alzheimer\u2019s, Parkinson\u2019s, and other neurological disorders can be seen as \u201cdirty brain\u201d diseases, where the brain struggles to clear out harmful waste. Aging is a key risk factor because, as we grow older, our brain\u2019s ability to remove toxic buildup slows down. However, new research in mice demonstrates that it\u2019s possible to reverse age-related effects and restore the brain\u2019s waste-clearing process.<\/p>\n<p>\u201cThis research shows that restoring cervical lymph vessel function can substantially rescue the slower removal of waste from the brain associated with age,\u201d says <a href=\"https:\/\/www.hajim.rochester.edu\/me\/people\/faculty\/kelley_doug\/index.html\">Douglas Kelley<\/a>, a professor of mechanical engineering at the <a href=\"https:\/\/www.rochester.edu\/\">University of Rochester<\/a>. \u201cMoreover, this was accomplished with a drug already being used clinically, offering a potential treatment strategy.\u201d<\/p>\n<p>Kelley is one of the lead authors of the study, which appears in the journal <a href=\"https:\/\/doi.org\/10.1038\/s43587-024-00691-3\"><em>Nature Aging<\/em><\/a>, along with <a href=\"https:\/\/www.urmc.rochester.edu\/people\/112359252-maiken-nedergaard\">Maiken Nedergaard,<\/a> codirector the University\u2019s <a href=\"https:\/\/www.urmc.rochester.edu\/ctn.aspx\">Center for Translational Neuromedicine<\/a>. The study is one of many collaborations carried out by researchers at Rochester\u2019s <a href=\"https:\/\/www.hajim.rochester.edu\/index.html\">Hajim School of Engineering &amp; Applied Sciences<\/a> and the <a href=\"https:\/\/www.urmc.rochester.edu\/about-us.aspx\">Medical Center<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alzheimer\u2019s, Parkinson\u2019s, and other neurological disorders can be seen as \u201cdirty brain\u201d diseases, where the brain struggles to clear out harmful waste. Aging is a key risk factor because, as we grow older, our brain\u2019s ability to remove toxic buildup slows down. However, new research in mice demonstrates that it\u2019s possible to reverse age-related effects [\u2026]<\/p>\n","protected":false},"author":701,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38,269,47],"tags":[],"class_list":["post-195994","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/195994","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/701"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=195994"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/195994\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=195994"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=195994"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=195994"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}