{"id":195234,"date":"2024-08-26T01:23:41","date_gmt":"2024-08-26T06:23:41","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/08\/scientists-discover-new-code-governing-gene-activity"},"modified":"2024-08-26T01:23:41","modified_gmt":"2024-08-26T06:23:41","slug":"scientists-discover-new-code-governing-gene-activity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/08\/scientists-discover-new-code-governing-gene-activity","title":{"rendered":"Scientists discover new code governing gene activity"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-discover-new-code-governing-gene-activity3.jpg\"><\/a><\/p>\n<p>A newly discovered code within DNA\u2014coined \u201cspatial grammar\u201d\u2014holds a key to understanding how gene activity is encoded in the human genome.<\/p>\n<p>This breakthrough finding, identified by researchers at Washington State University and the University of California, San Diego and <a href=\"https:\/\/www.nature.com\/articles\/s41586-024-07662-z\" target=\"_blank\">published<\/a> in <i>Nature<\/i>, revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists\u2019 understanding of <a href=\"https:\/\/medicalxpress.com\/tags\/gene+regulation\/\" rel=\"tag\" class=\"\">gene regulation<\/a> and how genetic variations may influence <a href=\"https:\/\/medicalxpress.com\/tags\/gene+expression\/\" rel=\"tag\" class=\"\">gene expression<\/a> in development or disease.<\/p>\n<p>Transcription factors, the proteins that control which genes in one\u2019s genome are turned on or off, play a crucial role in this code. Long thought of as either <a href=\"https:\/\/medicalxpress.com\/tags\/activators\/\" rel=\"tag\" class=\"\">activators<\/a> or repressors of gene activity, this research shows the function of transcription factors is far more complex.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A newly discovered code within DNA\u2014coined \u201cspatial grammar\u201d\u2014holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding, identified by researchers at Washington State University and the University of California, San Diego and published in Nature, revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-195234","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/195234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=195234"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/195234\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=195234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=195234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=195234"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}