{"id":193750,"date":"2024-07-30T02:22:28","date_gmt":"2024-07-30T07:22:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/07\/potential-therapeutic-target-for-age-related-macular-degeneration"},"modified":"2024-07-30T02:22:28","modified_gmt":"2024-07-30T07:22:28","slug":"potential-therapeutic-target-for-age-related-macular-degeneration","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/07\/potential-therapeutic-target-for-age-related-macular-degeneration","title":{"rendered":"Potential Therapeutic Target For Age-Related Macular Degeneration"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/BMkMAsSxVkU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>#eyehealth #aging #antiaging #cellularpathology #MacularDegeneration #AgeRelatedMacularDegeneration #retina #eyehealth #lysosomedysfunction #drusendeposits #stemcells #research<\/p>\n<hr>\n<p>A team of researchers reveals the cellular pathology of \u201cdry\u201d age-related macular degeneration (AMD); discovering the potential source of dysfunction in the process whereby cells in the retina remove waste.<\/p>\n<p><b>What<\/b><\/p>\n<p>The team from NIH and Johns Hopkins University, Baltimore, reported the details of how alterations in a factor called AKT2 affect the function of lysosome organelles, and results in the production of drusen deposits in the retina, which is a hallmark sign of dry age-related macular degeneration. The researchers suggest that the findings of drusen formation are a downstream effect of AKT2-related lysosome dysfunction and could point to a new target for therapeutic intervention.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>#eyehealth #aging #antiaging #cellularpathology #MacularDegeneration #AgeRelatedMacularDegeneration #retina #eyehealth #lysosomedysfunction #drusendeposits #stemcells #research A team of researchers reveals the cellular pathology of \u201cdry\u201d age-related macular degeneration (AMD); discovering the potential source of dysfunction in the process whereby cells in the retina remove waste. What The team from NIH and Johns Hopkins University, Baltimore, reported the details [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-193750","post","type-post","status-publish","format-standard","hentry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/193750","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=193750"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/193750\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=193750"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=193750"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=193750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}