{"id":193097,"date":"2024-07-18T00:23:22","date_gmt":"2024-07-18T05:23:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/07\/beyond-crispr-scientists-say-new-gene-editing-tool-is-like-a-word-processor-for-dna"},"modified":"2024-07-18T00:23:22","modified_gmt":"2024-07-18T05:23:22","slug":"beyond-crispr-scientists-say-new-gene-editing-tool-is-like-a-word-processor-for-dna","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/07\/beyond-crispr-scientists-say-new-gene-editing-tool-is-like-a-word-processor-for-dna","title":{"rendered":"Beyond CRISPR: Scientists Say New Gene Editing Tool Is Like a \u2018Word Processor\u2019 for DNA"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/hJ7zvZTxgT4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>\u201cBridge recombination can universally modify genetic material through sequence-specific insertion, excision, inversion, and more, enabling a word processor for the living genome beyond CRISPR,\u201d said Berkeley\u2019s Patrick Hsu, a senior author of one of the studies and Arc Institute core investigator, <a href=\"https:\/\/arcinstitute.org\/news\/news\/bridge\">in a press release<\/a>.<\/p>\n<p><b>CRISPR Coup<\/b><\/p>\n<p>Scientists first discovered CRISPR in bacteria defending themselves against viruses. In nature, a Cas9 protein pairs with an RNA guide molecule to seek out viral DNA and, when located, chop it up. Researchers learned to reengineer this system to seek out <em>any<\/em> DNA sequence, including sequences found in human genomes, and break the DNA strands at those locations. The natural machinery of the cell then repairs these breaks, sometimes using a provided strand of DNA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cBridge recombination can universally modify genetic material through sequence-specific insertion, excision, inversion, and more, enabling a word processor for the living genome beyond CRISPR,\u201d said Berkeley\u2019s Patrick Hsu, a senior author of one of the studies and Arc Institute core investigator, in a press release. CRISPR Coup Scientists first discovered CRISPR in bacteria defending themselves [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-193097","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/193097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=193097"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/193097\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=193097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=193097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=193097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}