{"id":192471,"date":"2024-07-07T14:22:30","date_gmt":"2024-07-07T19:22:30","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/07\/altos-rejuvenation-research-in-mice-signposts-healthspan-extension"},"modified":"2024-07-07T14:22:30","modified_gmt":"2024-07-07T19:22:30","slug":"altos-rejuvenation-research-in-mice-signposts-healthspan-extension","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/07\/altos-rejuvenation-research-in-mice-signposts-healthspan-extension","title":{"rendered":"Altos rejuvenation research in mice signposts healthspan extension"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/altos-rejuvenation-research-in-mice-signposts-healthspan-extension2.jpg\"><\/a><\/p>\n<p>So, they get very healthy but only live 24% longer no matter how many more times they use the treatment. I wonder what the telomere effect is. And what they are doing is not the same as what Aubrey\u2019s mouse experiment is doing.<\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/Elt4xGalQu4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<hr>\n<p>\n<a href=\"https:\/\/www.altoslabs.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altos Labs<\/a> Co-founder and Chief Scientist Rick Klausner participated in a panel discussing efforts to increase human healthspan by combatting age-related diseases at this year\u2019s <a href=\"https:\/\/www.youtube.com\/watch?v=Elt4xGalQu4&t=1s\" target=\"_blank\" rel=\"noreferrer noopener\">Aspen Ideas Health conference<\/a>.<\/p>\n<p>In a panel that included Laura Deming and Kristen Fortney, Klausner discussed an Altos experiment in Spain (likely to be research conducted by Universidad Cat\u00f3lica de Murcia and Altos Labs in collaboration with the Hospital Cl\u00ednic de Barcelona), Klausner reported that if old kidneys are transplanted into young people they do not function nearly as well as transplanting young kidneys \u2013 but organ donations donors are getting older and older, and therein lies the rub.<\/p>\n<p>We\u2019ve been doing these experiments with the transplant team at Barcelona where we remove a kidney from different animals, and now we\u2019re preparing to do this in the clinic. You take an old kidney and you transplant it into a young rat versus [transplanting] a young kidney and you see a tremendous difference in overall survival and kidney function. But when we take the old rat organ and we introduce these components that rejuvenate, this reprogramming cocktail, just for 45 minutes they\u2019re exposed to it and then they survive as well if not better than the young organs that are transplanted.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>So, they get very healthy but only live 24% longer no matter how many more times they use the treatment. I wonder what the telomere effect is. And what they are doing is not the same as what Aubrey\u2019s mouse experiment is doing. Altos Labs Co-founder and Chief Scientist Rick Klausner participated in a panel [\u2026]<\/p>\n","protected":false},"author":388,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-192471","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/192471","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/388"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=192471"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/192471\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=192471"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=192471"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=192471"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}