{"id":191625,"date":"2024-06-22T16:22:59","date_gmt":"2024-06-22T21:22:59","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/06\/principal-component-based-clinical-aging-clocks-identify-signatures-of-healthy-aging-and-targets-for-clinical-intervention"},"modified":"2024-06-22T16:22:59","modified_gmt":"2024-06-22T21:22:59","slug":"principal-component-based-clinical-aging-clocks-identify-signatures-of-healthy-aging-and-targets-for-clinical-intervention","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/06\/principal-component-based-clinical-aging-clocks-identify-signatures-of-healthy-aging-and-targets-for-clinical-intervention","title":{"rendered":"Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/principal-component-based-clinical-aging-clocks-identify-signatures-of-healthy-aging-and-targets-for-clinical-intervention2.jpg\"><\/a><\/p>\n<p>Using a dimensionality reduction approach, Fong <i>et al.<\/i> generated a clinical aging clock (PCAge) that delineates healthy and unhealthy aging trajectories. They provide a streamlined version (LinAge) that maintains predictive power, and they demonstrate how the clock can be tailored to available data using the CALERIE study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using a dimensionality reduction approach, Fong et al. generated a clinical aging clock (PCAge) that delineates healthy and unhealthy aging trajectories. They provide a streamlined version (LinAge) that maintains predictive power, and they demonstrate how the clock can be tailored to available data using the CALERIE study.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-191625","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/191625","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=191625"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/191625\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=191625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=191625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=191625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}