{"id":191036,"date":"2024-06-11T20:24:59","date_gmt":"2024-06-12T01:24:59","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/06\/2024-warren-alpert-prize-honors-four-pioneers-in-car-t-cell-therapy"},"modified":"2024-06-11T20:24:59","modified_gmt":"2024-06-12T01:24:59","slug":"2024-warren-alpert-prize-honors-four-pioneers-in-car-t-cell-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/06\/2024-warren-alpert-prize-honors-four-pioneers-in-car-t-cell-therapy","title":{"rendered":"2024 Warren Alpert Prize Honors Four Pioneers in CAR T-Cell Therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/2024-warren-alpert-prize-honors-four-pioneers-in-car-t-cell-therapy.jpg\"><\/a><\/p>\n<p>Significance of the work.<\/p>\n<p>CAR T cells are genetically engineered immune cells tailored to respond to a specific molecule found on the surface of tumor cells. These cells are a form of immunotherapy \u2014 an approach that harnesses the native ability of the immune system to fight diseases, particularly cancer. CAR T-cell therapy represents a milestone in cancer treatment. It propels cancer therapies beyond traditional chemotherapy and radiation treatments, which are often highly toxic and non-specific.<\/p>\n<p>The four scientists honored with this year\u2019s Warren Alpert Foundation Prize each played key distinct and complementary roles in developing CAR T cells and making their use in the clinic possible. Today, CAR T-cell therapies offer great hope for patients with various B-cell malignancies who have relapsed or failed to respond to other therapies. CAR T cell-based approaches could eventually be used to treat solid tumors, as well as a variety of autoimmune diseases and other conditions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Significance of the work. CAR T cells are genetically engineered immune cells tailored to respond to a specific molecule found on the surface of tumor cells. These cells are a form of immunotherapy \u2014 an approach that harnesses the native ability of the immune system to fight diseases, particularly cancer. CAR T-cell therapy represents a [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-191036","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/191036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=191036"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/191036\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=191036"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=191036"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=191036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}