{"id":190603,"date":"2024-06-04T14:30:16","date_gmt":"2024-06-04T19:30:16","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/06\/johns-hopkins-scientists-solve-30-year-biological-mystery-of-night-blindness"},"modified":"2024-06-04T14:30:16","modified_gmt":"2024-06-04T19:30:16","slug":"johns-hopkins-scientists-solve-30-year-biological-mystery-of-night-blindness","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/06\/johns-hopkins-scientists-solve-30-year-biological-mystery-of-night-blindness","title":{"rendered":"Johns Hopkins Scientists Solve 30-Year Biological Mystery of Night Blindness"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/johns-hopkins-scientists-solve-30-year-biological-mystery-of-night-blindness2.jpg\"><\/a><\/p>\n<p>In what they believe is a solution to a 30-year biological mystery, neuroscientists at <a href=\"https:\/\/scitechdaily.com\/tag\/johns-hopkins-medicine\/\">Johns Hopkins Medicine<\/a> say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.<\/p>\n<p>The condition, present from birth, causes poor vision in low-light settings.<\/p>\n<p>The findings, published May 14 in <em><i>Proceedings of the National Academy of Sciences<\/i><\/em>, demonstrate that the rhodopsin gene mutation, called G90D, produces an unusual background electrical \u201cnoise\u201d that desensitizes the eye\u2019s rods, those cells in the retina at the back of the eye responsible for nighttime vision, thus causing night blindness.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness. The condition, present from birth, causes poor vision in low-light settings. The [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-190603","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/190603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=190603"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/190603\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=190603"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=190603"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=190603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}