{"id":189722,"date":"2024-05-19T11:27:51","date_gmt":"2024-05-19T16:27:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/05\/vitamin-d-alters-mouse-gut-bacteria-to-give-better-cancer-immunity"},"modified":"2024-05-19T11:27:51","modified_gmt":"2024-05-19T16:27:51","slug":"vitamin-d-alters-mouse-gut-bacteria-to-give-better-cancer-immunity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/05\/vitamin-d-alters-mouse-gut-bacteria-to-give-better-cancer-immunity","title":{"rendered":"Vitamin D Alters Mouse Gut Bacteria to give Better Cancer Immunity"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/vitamin-d-alters-mouse-gut-bacteria-to-give-better-cancer-immunity.jpg\"><\/a><\/p>\n<p>Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH) and Aalborg University in Denmark have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.<\/p>\n<p>Reported today in Science, the researchers found that mice given a diet rich in vitamin D had better immune resistance to experimentally transplanted cancers and improved responses to immunotherapy treatment. This effect was also seen when gene editing was used to remove a protein that binds to vitamin D in the blood and keeps it away from tissues.<\/p>\n<p>Surprisingly, the team found that vitamin D acts on epithelial cells in the intestine, which in turn increase the amount of a bacteria called Bacteroides fragilis. This microbe gave mice better immunity to cancer as the transplanted tumours didn\u2019t grow as much, but the researchers are not yet sure how.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH) and Aalborg University in Denmark have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer. Reported today in Science, the researchers found that mice given [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1495],"tags":[],"class_list":["post-189722","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/189722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=189722"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/189722\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=189722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=189722"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=189722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}