{"id":189628,"date":"2024-05-17T19:28:57","date_gmt":"2024-05-18T00:28:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/05\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch"},"modified":"2024-05-17T19:28:57","modified_gmt":"2024-05-18T00:28:57","slug":"this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/05\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch","title":{"rendered":"This AI Just Designed a More Precise CRISPR Gene Editor for Human Cells From Scratch"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch3.jpg\"><\/a><\/p>\n<p>CRISPR was first discovered in bacteria as a defense mechanism, suggesting that nature hides a bounty of CRISPR components. For the past decade, scientists have screened different natural environments\u2014for example, pond scum\u2014to find other versions of the tool that could potentially increase its efficacy and precision. While successful, this strategy depends on what nature has to offer. Some benefits, such as a smaller size or greater longevity in the body, often come with trade-offs like lower activity or precision.<\/p>\n<p>Rather than relying on evolution, can we fast-track better CRISPR tools with AI?<\/p>\n<p>This week, <a href=\"https:\/\/www.profluent.bio\/\">Profluent<\/a>, a startup based in California, <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.04.22.590591v1\">outlined a strategy<\/a> that uses AI to dream up a new universe of CRISPR gene editors. Based on large language models\u2014the technology behind the popular ChatGPT\u2014the AI designed several new gene-editing components.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR was first discovered in bacteria as a defense mechanism, suggesting that nature hides a bounty of CRISPR components. For the past decade, scientists have screened different natural environments\u2014for example, pond scum\u2014to find other versions of the tool that could potentially increase its efficacy and precision. While successful, this strategy depends on what nature has [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,6],"tags":[],"class_list":["post-189628","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/189628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=189628"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/189628\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=189628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=189628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=189628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}