{"id":188171,"date":"2024-04-26T18:25:34","date_gmt":"2024-04-26T23:25:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/04\/cocas9-is-a-compact-nuclease-from-the-human-microbiome-for-efficient-and-precise-genome-editing"},"modified":"2024-04-26T18:25:34","modified_gmt":"2024-04-26T23:25:34","slug":"cocas9-is-a-compact-nuclease-from-the-human-microbiome-for-efficient-and-precise-genome-editing","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/04\/cocas9-is-a-compact-nuclease-from-the-human-microbiome-for-efficient-and-precise-genome-editing","title":{"rendered":"CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cocas9-is-a-compact-nuclease-from-the-human-microbiome-for-efficient-and-precise-genome-editing2.jpg\"><\/a><\/p>\n<p>Cas9 nucleases hold clinical significance for genome editing therapies. Here the authors characterize CoCas9, a compact, efficient and precise Cas9 from the human microbiome, and show that delivery via AAV vectors enables efficient editing in the mouse retina, expanding the genome editing toolbox.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cas9 nucleases hold clinical significance for genome editing therapies. Here the authors characterize CoCas9, a compact, efficient and precise Cas9 from the human microbiome, and show that delivery via AAV vectors enables efficient editing in the mouse retina, expanding the genome editing toolbox.<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-188171","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/188171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=188171"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/188171\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=188171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=188171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=188171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}