{"id":186858,"date":"2024-04-05T16:25:07","date_gmt":"2024-04-05T21:25:07","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/04\/revitalizing-vision-metabolome-rejuvenation-can-slow-retinal-degeneration"},"modified":"2024-04-05T16:25:07","modified_gmt":"2024-04-05T21:25:07","slug":"revitalizing-vision-metabolome-rejuvenation-can-slow-retinal-degeneration","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/04\/revitalizing-vision-metabolome-rejuvenation-can-slow-retinal-degeneration","title":{"rendered":"Revitalizing Vision: Metabolome Rejuvenation Can Slow Retinal Degeneration"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/revitalizing-vision-metabolome-rejuvenation-can-slow-retinal-degeneration2.jpg\"><\/a><\/p>\n<p>Gene therapy may be the best hope for curing retinitis pigmentosa (RP), an inherited condition that usually leads to severe vision loss and blinds 1.5 million people worldwide.<\/p>\n<p>But there\u2019s a huge obstacle: RP can be caused by mutations in over 80 different genes. To treat most RP patients with gene therapy, researchers would have to create a therapy for each gene\u2014a nearly impractical task using current gene therapy strategies.<\/p>\n<p>A more universal treatment may be forthcoming. Using CRISPR-based genome engineering, scientists at Columbia University Vagelos College of Physicians and Surgeons are designing a gene therapy with the potential to treat RP patients regardless of the underlying genetic defect.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gene therapy may be the best hope for curing retinitis pigmentosa (RP), an inherited condition that usually leads to severe vision loss and blinds 1.5 million people worldwide. But there\u2019s a huge obstacle: RP can be caused by mutations in over 80 different genes. To treat most RP patients with gene therapy, researchers would have [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412,269],"tags":[],"class_list":["post-186858","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=186858"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186858\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=186858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=186858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=186858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}