{"id":186518,"date":"2024-04-01T00:24:13","date_gmt":"2024-04-01T05:24:13","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2024\/04\/turning-back-the-clock-on-aging-immune-systems-new-treatment-rejuvenates-elderly-defenses"},"modified":"2024-04-01T00:24:13","modified_gmt":"2024-04-01T05:24:13","slug":"turning-back-the-clock-on-aging-immune-systems-new-treatment-rejuvenates-elderly-defenses","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2024\/04\/turning-back-the-clock-on-aging-immune-systems-new-treatment-rejuvenates-elderly-defenses","title":{"rendered":"Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/turning-back-the-clock-on-aging-immune-systems-new-treatment-rejuvenates-elderly-defenses2.jpg\"><\/a><\/p>\n<p>\ud83e\uddec\ud83d\udd2c\ud83d\udc01<\/p>\n<hr>\n<p>\n<b>The effects of aging on the immune system<\/b><\/p>\n<p>The aging immune system is associated with reduced lymphopoiesis, increased inflammation, and myeloid diseases due to alterations in self-renewing HSCs. During childhood, bal-HSCs predominate, thereby facilitating lymphopoiesis and adaptive immune responses.<\/p>\n<p>Age increases my-HSCs, which reduces lymphopoiesis and enhances myelopoiesis. Myeloid-HSC origin and possible interconversions are unclear; however, removing my-HSCs in aged mice may reverse the aging phenotype.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud83e\uddec\ud83d\udd2c\ud83d\udc01 The effects of aging on the immune system The aging immune system is associated with reduced lymphopoiesis, increased inflammation, and myeloid diseases due to alterations in self-renewing HSCs. During childhood, bal-HSCs predominate, thereby facilitating lymphopoiesis and adaptive immune responses. Age increases my-HSCs, which reduces lymphopoiesis and enhances myelopoiesis. Myeloid-HSC origin and possible interconversions are [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-186518","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186518","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=186518"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/186518\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=186518"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=186518"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=186518"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}